StillPeaks Virtual GC is a digitized model of your Gas Chromatograph (GC) and constructs chromatograms based on separation science.
It’s primary purpose is to simulate and optimize your GC. Next to that it is a great booster for any Detailed Hydrocarbon Analysis software.
Developing a Temperature Programmed GC method (TPGC method) is easier then ever with Virtual GC. You optimize for quick separations and minimized coelutions in a few mouse clicks.
Now Method Developers can easily, quickly and accurately develop and translate TPGC methods. So do your R&D on your PC and apply the relevant methods on your GC…
Virtual GC explained
This software is based on the Kovats index concept and separation science (retention time, flow relations and efficiency).
The n-alkanes and temperature programmed GC (TPGC) Kovats indices with coelution detection are being calculated from Kovats Isothermal Data (KID) and your GC method input (your temperature program, column dimensions, gastypes, velocity, pressure, etc).
Outlet flow, splitter vent flow and inlet pressure are calculated from the viscosity of Hydrogen, Helium and Nitrogen.
Temperature Programmed versus Isothermal Kovats Data
Kovats Isothermal Data is the most constant retention parameter and it’s independent of stationary phase film thickness and gas velocity. While Temperature Programmed GC (TPGC) Kovats index is widely used. Unfortunately TPGC indices are more sensitive to the gas velocity, film thickness and temperature program of your GC. Therefor StillPeaks decided to recalculates these TPGC indices based on your settings and by doing so dynamically building new databases for you.
By changing your GC method configuration in Virtual GC (your temperature program, column dimensions, gastypes, velocity, pressure, etc) the n-alkanes and temperature programmed GC Kovats indices are being recalculated. This way you can fine-tune it close to perfectly.
Virtual GC as add-on for your DHA software
Peak identification software use retention times for peak identification. Every GC has slightly different retention times, so every GC identifies peaks slightly differently. Detailed Hydrocarbon Analysis (DHA) software often uses a combination of shortlists, patterns and a Kovats database. This provides much better results, but still leaves room for improvement.
StillPeaks Virtual GC software is an add-on to improve peak identification in any DHA-software. In stead of manually tuning the peaks Virtual GC can calculate the n-alkanes and the TPGC Kovats Data with coelution detection from GC method input and Kovats Isothermal Data.
For matching the calculated and measured chromatograms the Virtual GC configuration of course needs to match your physical GC method.
Virtual GC in Hydrocarbon mode as Method Development tool
For Detailed Hydrocarbon Analysis (DHA) the configuration in Virtual GC should match a physical GC method. By changing the Virtual GC configuration settings in any way it recalculates the TPGC Kovats Data with coelution detection. And by doing so you have a perfect Method Development tool for peak identification with different GC Methods.
Virtual GC is an extensive optimization and method translator tool with separation information. It has the benefit of calculating the optimum before the actual lab experiment, speeding up TPGC methods, increase sample throughput and reduce footprint, so you use less GC-time for your workload because you can focus on the selected options from your list of experiments calculated with our software.
With the computed model of StillPeaks Virtual GC you can decrease the number of trial and error runs in your lab. You can run hundreds of method translation experiments on your computer, select the best ones in a blink and run them on your physical GC to compare chromatograms. That will save you extensive lab time!
Virtual GC as training and education tool
Next to changing the settings in Virtual GC to define an optimized method, changing the settings also explains the basics of Gas Chromatography. Virtual GC simulates Gas Chromatography and in doing so it’s an outstanding training and educational tool.
Explain Gas Chromatography and have students run their experiments digitally (and possibly remote) with Virtual GC software. Students of all levels can benefit from this. Beginners can learn the basics of Gas Chromatography. More advanced users can learn to optimize and practice method development skills.
ASTM D6730 optimization
ASTM method D6730 is also known as Neil Johansen Extended Detailed Hydrocarbon Analysis (DHA-X). Although this ASTM D6730 method is defined with a fixed set of rules it provides the flexibility for changing pre-column length and temperature programming and this changes the TPGC Kovats Data.
StillPeaks Virtual GC can use polar pre-column input to recalculate the TPGC Kovats Data to indentify your target compounds on TPGC.
Expanding the scope
Currently the scope of the Kovats Isothermal Data (KID) in StillPeaks Virtual GC is 240 hydrocarbons up to C10 on Phenyl-Methyl-Silicone stationary phases (0…75% Phenyl). Within this scope separations and coelutions can be successfully identified.
New Kovats Isothermal Data compilations extends the scope from refinery samples to new applications like mineral oils, new fuels, fragrances, solvents, herbicides, pesticides, fire retardants, etc.
This is work in progress. Please feel encouraged to send us your input for these extensions.
See one or more of our informative video’s to get an impression of Virtual GC: